EUTYLONE HYDROCHLORIDE | C₁₃H₁₇NO₃

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Eutylone hydrochloride, scientifically known as β-keto-1,3-benzodioxolyl-N-ethylbutanamine, is a synthetic cathinone and β-keto amphetamine analog with the molecular formula C₁₃H₁₇NO₃ and a molecular weight of 235.28 g/mol. Structurally, it features a 3,4-methylenedioxy-substituted phenyl ring attached to a butanone backbone with an ethyl amino substituent, distinguishing it from other cathinones.
It is structurally similar to other well-known drugs such as MDMA (Ecstasy) and methylenedioxypyrovalerone (MDPV).

Pharmacologically, eutylone acts as a monoamine transporter inhibitor, primarily targeting dopamine (DAT), norepinephrine (NET), and serotonin (SERT) transporters. Studies show it induces locomotor stimulation in vivo, a hallmark of psychostimulants.

Effects and Risks

Eutylone acts on the brain’s neurotransmitter systems, particularly affecting dopamine, serotonin, and norepinephrine levels. Users report effects similar to those of other stimulants, including increased energy, euphoria, and enhanced sociability. However, it also poses significant health risks, including
Agitation and anxiety
Hypertension and tachycardia
Hyperthermia and seizures
Potential for overdose and death.

Research Applications of Eutylone

Eutylone has shown significant value in controlled lab settings, particularly in:

Neurochemical transporter studies—analyzing dopamine, norepinephrine, and serotonin reuptake
Forensic analysis—case simulations involving cathinone-related compounds
Analytical instrumentation calibration—HPLC, MS, and GC-MS profiling
In vitro receptor studies—SAR and ligand binding efficiency

Its high affinity and activity in monoaminergic systems provide critical insight for researchers studying psychostimulant behavior.